Table of Contents
Volume8, issue 2; July 31; 2025
https-dx-doi-org-10-31183-imcp-2025-v8i2

Research Article

1- Inhibitors of Plasmodium falciparum dihydrofolate reductase-thymidylate synthase: In-silico evaluation of phenylpiperazinyl derivatives
Authors: Oluwafemi S. Aina; Mujeeb O. Rofiu; Kafayat A. Owoseni-Fagbenro; Luqman A. Adams; Oluwole B. Familoni. Investigational Medicinal Chemistry and Pharmacology 2025 8(2):109. doi: https://dx.doi.org/10.31183/imcp.2025.00109

2- Antidiabetic effects of Cassia abbreviata Oliv. leaf fractions extracts in type 2 diabetic male adult Wistar rats
Authors: Emmanuel M. Musenge; Lavina Prashar; Sergio Muwowo; Isaac Mweemba, Victoria Mwiinga-Kalusopa; Marie-Claire Uwamahoro; and Fastone M. Goma. Investigational Medicinal Chemistry and Pharmacology 2025 8(2):110. doi: https://dx.doi.org/10.31183/imcp.2025.00110

3- Antibacterial activity and antibiotic-potentiating effects of Termnalia laxiflora and Azadirachta indica against multidrug-resistant Staphylococcus aureus
Authors: Larissa Mpude; Eric Cadet; Derick J. Assonfack; Ancela W. B. Yendze; Jenifer R. N. Kuete; Valaire Y. Matieta; Junior F. Megaptche; Michael F. Kengne; Idrios N. Bonsou; Armelle T. Mbaveng; and Victor Kuete. Investigational Medicinal Chemistry and Pharmacology 2025 8(2):111. doi: https://dx.doi.org/10.31183/imcp.2025.00111

4- Anti-inflammatory, analgesic, and antipyretic activities of aqueous and methanol stem bark extracts of Drypetes gossweileri in persistent inflammatory pain induced by complete Freund’s adjuvant in rats
Authors: Francis Desire Tatsinkou Bomba; Uzuegbu Esther Nyechukwu; Bibiane Aimee Wandji; Erastus Nembu Nembo; Armel Jackson Seukep; Arnaud Fodjo Kouam; Marius Mbiantcha; Telesphore Benoit Nguelefack; and Emmanuel Acha Asongalem.
Investigational Medicinal Chemistry and Pharmacology 2025 8(2):112. doi: https://dx.doi.org/10.31183/imcp.2025.00112

5- Ethanolic leaf extract of Crinum distichum reverses carbon tetrachloride-induced hepatic fibrosis in rats
Authors: Melanie Numbu; Arnaud Kouam Fondjo; Eleonore Ngounou; Elisabeth Menkem Zeuko’o; Branly-natalien Nguena-dongue; Napoleon Mfonku; and Gregory Edie Halle-Ekane. Investigational Medicinal Chemistry and Pharmacology 2025 8(2):113. doi: https://dx.doi.org/10.31183/imcp.2025.00113

6- Comparative effects of oral antidiabetic regimens, exercise and BMI on glycemic control and organ function in type 2 diabetes mellitus patients in Bamenda, Cameroon
Authors: Junior Tegha Kum Muankang; Andre Gilles Mache; Aphrodite Choumessi Tchewonpi; Olivia Maih Tim; Christian Fusi Suh; Faustin Pascal Manfo Tsague; Promise Penn Muluh; Edouard Nantia Akono. Investigational Medicinal Chemistry and Pharmacology 2025 8(2):114. doi: https://dx.doi.org/10.31183/imcp.2025.00114

7- In vitro antiplasmodial, anthelmintic activities and toxicological profile of the leaves, roots, and stem bark of Ficus bubu Warb.
Authors: Eugène Ekounè Kamè; Edwige Laure Nguemfo; Sandrine Evelyne Nsango; Lawrence Ayong; Else Carole Eboumbou Moukoko; Giselle Marie Marguerite Etamè Loe; and Jean Emmanuel Mbosso Teinkela. Investigational Medicinal Chemistry and Pharmacology 2025 8(2):115. doi: https://dx.doi.org/10.31183/imcp.2025.00115

8- Acute toxicity evaluation of Opuntia stricta Cladode grown in Zambia on Wistar albino rodents
Authors: Martin Kampamba; Christian Chinyere Ezeala; Kadango Zombe; and Angela Gono Bwalya. Investigational Medicinal Chemistry and Pharmacology 2025 8(2):116. doi: https://dx.doi.org/10.31183/imcp.2025.00116

9- Investigation of insulin resistance and glycemic response to Dennettia tripetala essential oil in steptozocin-induced diabetic mice
Authors: Tajudin Adesegun Adetunji; Abiodun Kofoworola Ajeigbe; Ummulkhair Funke Adetunji; and Idris Ajayi Oyemitan. Investigational Medicinal Chemistry and Pharmacology 2025 8(2):117. doi: https://dx.doi.org/10.31183/imcp.2025.00117

10- Translational preclinical evaluation of Strychnos innocua leaf extract: Investigating anti-nociceptive and antidepressant activities using in vivo and in silico models
Authors: Chinedu Enegide; Eugene Ehimare; Divine Odeworitse; Ujunwa Emelda Ezeanochie; Israel Ofejiro Efejene; Michael Eromosele Aisuodionoe; Osasengo Precious Osifo; Esther Adaeze Ossai; Emmanuella Chukwufumnanya Nwegbu; Sophia Onyinyechi Agundu; and Jennifer Orevaoghene Etiku. Investigational Medicinal Chemistry and Pharmacology 2025 8(2):118. doi: https://dx.doi.org/10.31183/imcp.2025.00118

11- Callistemon citrinus essential oil from Cameroon: potent inhibitor of bacterial respiratory pathogens without inducing resistance or persistence
Authors: Marc Flaubert Yumsu Tcham; Ebenezer Tatiekam Foka; Cedric Fossi Tchinda; Armelle Deutou Tchamgoue; Véronique Beng Penlap; and Jean Paul Assam Assam. Investigational Medicinal Chemistry and Pharmacology 2025 8(2):119. doi: https://dx.doi.org/10.31183/imcp.2025.00119