Abstract
Background: The global burden of bacterial infections remains a serious health concern. In the present review, we have summarized the best botanicals and phytochemicals from the flora of Africa that deserve clinical studies to develop novel antibacterial drugs to combat enterobacteria, Pseudomonas aeruginosa, Gram-positive bacteria, and mycobacteria.
Methods: Data were retrieved from scientific databases such as PubMed, Scopus, ScienceDirect, Google Scholar, and Web of Science us...
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Review article
Inorganic Compounds Utilized in Cancer Therapy: A Comprehensive Review
Abstract
Background: Cancer is the most feared disease, with more than 1.6 million cases yearly. Cancer can start almost anywhere in the human body, from the uncontrollable growth and multiplication of damaged cells. Cancerous tumors can spread into the human body (a process called metastasis) in a solid form usually, but the cancers of the blood generally do not.
Methods: The review analyzes a wide range of scientific literature and research studies to assess the efficacy and mechanisms ...
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Phytochemistry and pharmacology of Imperata cylindrica: A comprehensive review
Abstract
Background: Imperata cylindrica is a medicinal spice used in traditional medicine to cure several ailments including cancer, wounds, hypertension, and inflammation. The current study aimed to compile phytochemicals and pharmacological data on Imperata cylindrica.
Methods: A bibliographic study was carried out by analyzing conventional textbooks, authentic published studies, and consulting wide-reaching accepted scientific databases. In this review, an attempt is being made to est...
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Chemical constituents and antibacterial activity from the fruits of Ficus sur Forssk
Abstract
Background: Ficus sur Forssk is used in traditional African medicine in the treatment of skin diseases, epilepsy, jaundice, pain, inflammation, anemia, sexually transmitted diseases, and diarrhea. We described here the chemical study and antibacterial properties of F. sur ethanol extract.
Methods: Separation and isolation of compounds were performed using common chromatographic methods. The structures of compounds were determined by spectrometric and spectroscopic analyses includ...
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Antibacterial, antioxydant and antidiarrheal properties of Tristemma hirtum P. beauv.
Abstract
Background: The aim of this study was to investigate the antibacterial, radical-scavenging and antidiarrheal properties of Tristemma hirtum.
Methods: The methanol extract of Tristemma hirtum was prepared by successive fractionation in hexane and ethyl acetate solvents. The phytochemical composition of crude extract and fractions was studied using standard methods. Their antimicrobial activities were evaluated against Gram-negative and Gram-positive species of pathogenic bacteria ...
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Interleukin-8 in Tissue Injury and Inflammation
Abstract
Background: Inflammation is a vascular or tissue response that occurs as a result of infection, tissue injury or irritation. The review is aimed at describing the functions of Interleukin-8 (IL-8) and its role in tissue injury and inflammation.
Methods: Articles were searched from the internet using the following search words; Inteluekin-8, IL-8 structure and functions, role of IL-8 in tissue injury, inflammation and inflammatory response, IL-8 in hepatic, nervous, cardiac and ki...
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