Abstract   Background: The effectiveness of antibiotics in the fight against bacterial infections motivated their massive use which resulted in the appearance of resistant bacteria. This phenomenon is nowadays in constant evolution and represents a major problem of public health. In this respect, the search for new molecules for fighting against bacterial resistance is essential. This work was committed to studying the in vitro antibacterial activity of the ethanol crude extract, fra...

Abstract Background: This work evaluated the antipsychotic and anticonvulsant effects of crude aqueous leaf extract of Vitex doniana in mice. This was to validate the use of V. doniana in the treatment of mental disorders and epilepsy in folkloric medicine. Methods: Antipsychotic effect of V. doniana was evaluated using the animal models of psychosis: swimming-induced grooming, ketamine-induced hyperlocomotion and apomorphine-induced climbing tests. Anticonvulsant effect was evaluated usi...