Analgesic and anti-inflammatory activities of roots aqueous extract of Pseudospondias microcarpa (A. Rich.) Engl. (Anarcadiaceae) in mice and rats

Abstract Background: Pseudospondias microcarpa (P. microcarpa) is a tree belonging to the family Arnacardiaceae. This species is used in traditional medicine to treat pain, inflammation, malaria, and skin diseases. The present study was undertaken to evaluate the analgesic and anti-inflammatory properties of the aqueous extract of P. microcarpa roots. Methods: Swiss mice and Wistar albino rats were used for the study. The aqueous extract (100, 300, and 600 mg/kg), standards, and water wer...
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Antibacterial and antibiotic-potentiating activities of nine Cameroonian medicinal plants against multidrug-resistant bacteria expressing active efflux pumps

Abstract Background: In the last ten years, the resistance of Gram-negative and Gram-positive bacteria continuously increased. The present study was designed to evaluate the antibacterial and antibiotic-potentiating activities of nine Cameroonian medicinal plants: Cucumeropsis mannii, Lagenaria siceraria, Citrullus lanatus, Cucurbita moschata, Salix ledermannii, Gouania longispicata, Psychotria mapourioides, Conyza aethiopica and Conyza sumatrensis against resistant phenotypes. Methods: L...
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Efficacy and persistence of essential oil of Monodora myristica against Anopheles gambiae, the main vector of malaria in sub-Saharan Africa

Abstract Background: Monodora myristica known as calabash or nutmeg, is a tree of the Annonaceae family whose seeds are mainly used as a spice. The control of malaria is still a challenge partly due to mosquito resistance to conventional insecticides. The present work aimed to evaluate the insecticidal effect of the essential oil of M. myristica seeds to enlarge the list of local plants that can be used as insecticides. Methods: Essential oil was extracted by hydrodistillation using the C...
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