Chemical constituents and antibacterial activity of Annickia chlorantha (Oliv.) Setten & Maas (Annonaceae) and their chemophenetic significance

-Vidal Leudja Noume; Raymond Ngansop Nono; Jean F. Zeutsop; Appolinaire Kene Dongmo; Jean R. Chouna; Pépin Nkeng-Efouet-Alango.

Abstract Background: Annickia chlorantha (Annonaceae) is an ornamental tree, which may grow up to 30 m high with dense foliage and spreading crown. It is used in traditional medicine for its anti-infective properties particularly in the treatment of fungal infections, malaria, hepatitis, jaundice and other bacterial infections. This study describes the chemical and antibacterial investigation of ethanol extract of the stem bark of A. chlorantha. Methods: The compounds were obtained by sep...

Antibacterial and antibiotic-potentiation activity of Coffea arabica and six other Cameroonian edible plants against multidrug-resistant phenotypes

-Louise S. Moungoue Ngwaneu; Armelle T. Mbaveng; Paul Nayim; Brice E. N. Wamba; Laetitia M. Youmbi; Idrios N. Bonsou; Fred Ashu; Victor Kuete

Abstract Background: Medicinal plants have always played an important role in human health. Many plants are traditionally used as drugs against microbial infections. In this study, a panel of seven methanol extracts from Cameroonian edible was assessed for their antibacterial potentiality against multidrug-resistant Gram-positive and Gram-negative bacteria. Methods: The microdilution technique using a 96-well plate was used to assess the minimal inhibitory concentration (MIC) and minimal ...

Comparative study of polyphenols quantification, total phenolic content, and antioxidant activities of the fruits of three plants of the family of Solanaceae: Lycium ruthenicum, Lycium barbarum, and Lycium Chinense

-Irma B. Yossa Nzeuwa; Fatimata Nea; Junelle Makemteu; Gella M. Ngandeu Neubi; Florence D. Mabou; Jaures A. Noumedem Kenfack; Doriane E. Djeussi; Guiju Sun.

Abstract Background: Fruits from L. ruthenium, L. barbarum, and L. Chinense, of the family Solanaceae are well-known in traditional Chinese medicine and have been used as popular functional foods, with a large variety of beneficial health effects. Methods: In The present study, ethanolic extracts (30%) of lycium fruits were analyzed by high-performance liquid chromatography (HPLC). Total phenolic content was determined together with the quantification of seventeen (17) phenolic compounds....

Cellular modes of action of the methanol extract from the aerial parts of Psychotria sycophylla (K.Schum.) Petit (Rubiaceae) against multidrug-resistant bacteria

-Olive Monique F. Demgne; Cedric F. Tchinda; Armelle T. Mbaveng; Michel-Gael F. Guefack; Veronique P. Beng; Victor Kuete.

Abstract Background: Infectious diseases caused by multidrug-resistant bacteria (MDR) remain a global health issue. The population uses several plants from the Cameroonian pharmacopeia to treat bacterial infections. The methanol extract from the aerial parts of Psychotria sycophylla (K.Schum.) Petit (Rubiaceae) (PSA) previously showed antibacterial activities against MDR bacteria. In the present study, the antibacterial activities of PSA were determined in the presence of an efflux pump inhi...

Diversity of aggressive Aedinian fauna and susceptibility of Aedes albopictus (Skuse, 1894) to Ageratum conyzoides L., 1753 and Chromolaena odorata L. Robinson, 1970 (Asteraceae) essential oils in some towns from southern Cameroon

-Odette E. Ngo Hondt; Patrick Akono-Ntonga; Henri G. Tsila; Francis N. Nopowo Takap; Willy Soh Teukam; Rachel Ngaha; Leger Offono Enama; Romeo S. Mbongue; Wolfgang Eyisap Ekoko; Victor D. Moussango; Armel Tedjou Nouboudem; Edmond Kopya; Agnes A. Ntoumba; Fabrice Monkam Tchamaha; Abdou Talipouo; Herman P. Awono Ambeme; Léopold G. Lehman.

Abstract Background: A good knowledge of Aedes diversity and their biting cycle is necessary for better planning of vector control interventions against arboviruses diseases. This study aims to determine the diversity of Aedes and the biting cycle of Aedes albopictus in suburban as well as urban areas of Douala, Kribi, and Ayos to propose a method for vector control based on Ageratum conyzoides L., 1753 and Chromolaena odorata L., 1970 (Asteraceae) essential oil. Methods: Larvae were sam...