Anthelmintic effect of Portulaca oleracea Linne (Portulacacea) against gastrointestinal parasites Haemonchus contortus Rudolphi and toxicity screenings

-Ahmadou Adamou; Issiyakou Haman; Francis Nveikoueing; Irene Ajonina-Ekoti; Toua Vroumsia; Dieudonné Ndjonka

Abstract Background: The resistance of gastrointestinal worms to synthetic anthelmintics (Levamisole) leads us to highlight the Cameroonian pharmacopoeia. The main objective of the present work is to look for an alternative treatment for haemonchosis, based on active secondary metabolites, from Portulaca oleracea, with less or no side effects and accessible to all. Methods: The Haemonchus contortus cycle test was performed at varying concentrations. Levamisole and PBS were the positive an...

GC-MS analysis and physiochemical properties of Enterolobium cyclocarpum (elephant ear) seed oil

-Opeyemi N. Avoseh; Zacheus M. Akinpelu; Olawale L. Osifeko; Folajimi T. Arubuola; Fanyana M. Mtunzi; Isiaka A. Ogunwande.

Abstract Background: The present study aimed to extract, evaluate the physicochemical properties, and chemical characterization of the seed Enterolobium cyclocarpum. E. cyclocarpum is a legume of the Leguminosae family. It is used as foliage, for animal feeding and oil is extracted for several application in folk medicine for the treatment of sore throat, colds, diarrhea, headache, intestinal ailments, and stomachache. The leaf infusion is used as a laxative In the West Indies; seeds are che...

Testicular antioxidants and testosterone enhancing effects of the hydro-ethanolic extract of Rauvolfia vomitoria (Apocynacaea) in male Wistar rats

-Antoine S. Kada; Emmanuel Aneng; Mariama Mbouh; Faustin P. T. Manfo; Stanley N. Ngimgoh; Edouard A. Nantia

Abstract Background: Natural products such as extracts of plants have been seen as a possible alternative to conventional therapies in the treatment and management of male infertility. This study aimed at investigating the testicular antioxidant and testosterone enhancing ability of the hydro-alcoholic extract of Rauvolfia vomitoria in male rats. Methods: Twenty-four male rats were divided into four groups of 6 rats each, treated daily with either vehicle (distilled water; 5 mL/kg) or hyd...

Phytochemical analysis and antibiotic-modulating activity of Cocos nucifera, Glycine max and Musa sapientum methanol extracts against multidrug resistant Gram-negative bacteria

-Carine M.N. Ngaffo; Simplice B. Tankeo; Michel-Gael F. Guefack; Brice E. N. Wamba; Paul Nayim; Idrios N. Bonsou; Victor Kuete; Armelle T. Mbaveng.

Abstract Background: The rapid emergence of multidrug resistant (MDR) bacteria is occurring worldwide, endangering the efficacy of antibiotics, which have transformed medicine and saved millions of lives. Antibiotic-resistant infections are already widespread in the Sub-Saharan Africa and across the globe. To extend the search for new and more efficient antimicrobial drugs from natural sources, this work has been carried out to study the phytochemical composition and the antibacterial activi...