Abstract Background: Liver diseases account for approximately one-third of all mortality in tropical countries, many of which are of significant research interest. This study investigated the effects of the hydromethanolic leaf extract of Craterispermum schweinfurthii on liver function using Wistar rats as experimental models. Methods: Twenty female Wistar rats weighing between 100 and 250 g were randomly divided into four groups of five rats each and treated daily for 28 days as follows:...

Abstract Background: Metabolic syndrome is a major public health concern, often exacerbated by patients’ difficulty in adhering to restrictive diets. This study proposes an innovative dietary approach by developing low-glycemic-index biscuits specifically formulated to support the management of this condition. Methods: The phytochemical-enriched formulations were produced using composite flours of sweet potato (Ipomoea batatas (L.)) (60 - 65%), carrot (Daucus carota subsp. sativus) (15 - ...

Abstract Background: Intrauterine growth restriction (IUGR) is associated with placental oxidative stress and inflammation, contributing to poor pregnancy outcomes. Phyllanthus muellerianus is a medicinal plant rich in bioactive compounds with reported antioxidant and anti-inflammatory effects. This study investigated the effects of Phyllanthus muellerianus extracts in a rat model of chronic restraint stress (CRS)-induced IUGR. Methods: Thirty-five pregnant rats were exposed to CRS (6h/da...