Effect of a phytochemical-enriched functional food formulation from Ipomoea batatas, Daucus carota subsp. sativus, and Gnetum africanum on metabolic syndrome in Wistar Rats

-Clautilde Teugwa Mofor; Archimede Koumagueyeng; Denis Zofou; Florian Amel Tekou; and Jean Paul Dzoyem

Abstract Background: Metabolic syndrome is a major public health concern, often exacerbated by patients’ difficulty in adhering to restrictive diets. This study proposes an innovative dietary approach by developing low-glycemic-index biscuits specifically formulated to support the management of this condition. Methods: The phytochemical-enriched formulations were produced using composite flours of sweet potato (Ipomoea batatas (L.)) (60 - 65%), carrot (Daucus carota subsp. sativus) (15 - ...

Phyllanthus muellerianus Kuntze exell (Euphorbiaceae) improves maternal reproductive outcomes, fetal growth, and modulates placental oxidative stress/inflammation in a rat model of intrauterine growth restriction

-Henderson Herris Karl Zeugang Ngombeu; Aubrile Julie Ndomgang; Georges Roméo Bonsou Fozin; Mama Sy; Prechmy Carole Ngueyong Nsamou; Aimé Césaire Momo Tetsatsi; and Pierre Watcho

Abstract Background: Intrauterine growth restriction (IUGR) is associated with placental oxidative stress and inflammation, contributing to poor pregnancy outcomes. Phyllanthus muellerianus is a medicinal plant rich in bioactive compounds with reported antioxidant and anti-inflammatory effects. This study investigated the effects of Phyllanthus muellerianus extracts in a rat model of chronic restraint stress (CRS)-induced IUGR. Methods: Thirty-five pregnant rats were exposed to CRS (6h/da...