Abstract
Background: Metabolic syndrome is a major public health concern, often exacerbated by patients’ difficulty in adhering to restrictive diets. This study proposes an innovative dietary approach by developing low-glycemic-index biscuits specifically formulated to support the management of this condition.
Methods: The phytochemical-enriched formulations were produced using composite flours of sweet potato (Ipomoea batatas (L.)) (60 - 65%), carrot (Daucus carota subsp. sativus) (15 - ...
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Volume 9, issue 2; July 31; 2026
https-dx-doi-org-10-31183-imcp-2026-v9i2
Research Article
1- Phyllanthus muellerianus Kuntze exell (Euphorbiaceae) improves maternal reproductive outcomes, fetal growth, and modulates placental oxidative stress/inflammation in a rat model of intrauterine growth restriction
Authors: Henderson Herris Karl Zeugang Ngombeu; Aubrile Julie Ndomgang; Georges Roméo Bonsou Fozin; Mama Sy; Prechmy Carole Ngueyong Nsamou; Aimé Césaire Momo Tetsatsi; and Pierre Watcho. Investigational Medicinal Chemistry and Pharmacology 2026 9(2):137. doi: https://dx.doi.org/10.31183/imcp.2026.00137
2- Effect of a phytochemical-enriched functional food formulation from Ipomoea batatas, Daucus carota subsp. sativus, and Gnetum africanum on metabolic syndrome in Wistar Rats
Authors: Clautilde Teugwa Mofor; Archimede Koumagueyeng; Denis Zofou; Florian Amel Tekou; and Jean Paul Dzoyem. Investigational Medicinal Chemistry and Pharmacology 2026 9(2):138. doi: https://dx.doi.org/10.31183/imcp.2026.00138
Phyllanthus muellerianus Kuntze exell (Euphorbiaceae) improves maternal reproductive outcomes, fetal growth, and modulates placental oxidative stress/inflammation in a rat model of intrauterine growth restriction
Abstract
Background: Intrauterine growth restriction (IUGR) is associated with placental oxidative stress and inflammation, contributing to poor pregnancy outcomes. Phyllanthus muellerianus is a medicinal plant rich in bioactive compounds with reported antioxidant and anti-inflammatory effects. This study investigated the effects of Phyllanthus muellerianus extracts in a rat model of chronic restraint stress (CRS)-induced IUGR.
Methods: Thirty-five pregnant rats were exposed to CRS (6h/da...
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